Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690085 | 0.89 | PKM (0.51) | KDM4ELMNAALDH1A1HPGDTSHR | |
| SCHEMBL9473905 | 0.83 | ALDH1A1 (0.51) | ATMKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL9688157 | 0.81 | KDM4E (0.49) | KDM4ELMNAALDH1A1HPGDTSHR | |
| SCHEMBL9869972 | 0.78 | ATM (0.43) | KMT2AATMKDM4ELMNAALDH1A1 | |
| SCHEMBL11709161 | 0.76 | GAA (0.54) | ATMKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL11801987 | 0.76 | GAA (0.54) | KMT2AATMKDM4ELMNAALDH1A1 | |
| SCHEMBL9688992 | 0.75 | GAA (0.54) | ATMKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL27517088 | 0.74 | KDM4E (0.68) | KMT2AKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL9870900 | 0.73 | ATM (0.45) | KMT2AATMKDM4ELMNAALDH1A1 | |
| SCHEMBL10564440 | 0.73 | CACNA1F (0.61) | KDM4EALDH1A1HPGDGAACACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0158211-B1 | 1,4-DIHYDROPYRIDIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USES AS MEDICAMENTS | LABORATORIOS DELAGRANGE S.A. (ES) | 1992-08-26 | — | — | EP | disclosed |
| US-4722931-A | MUSCLE RELAXANTS | LABORATORIOS DELAGRANGE (ES) | 1988-02-02 | — | — | US | disclosed |
| EP-0158211-A2 | 1,4-Dihydropyridin derivatives, process for their preparation and their uses as medicaments | LABORATORIOS DELAGRANGE S.A. (ES) | 1985-10-16 | — | — | EP | disclosed |