Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 13/20 | 0.49 |
| ▸ | CASP5 | P51878 | 13/20 | 0.49 |
| ▸ | CASP4 | P49662 | 11/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | KMT5A | Q9NQR1 | 3/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690140 | 0.90 | MEN1 (0.47) | KMT5ATLR9TLR7MEN1CYP3A4 | |
| SCHEMBL9689154 | 0.82 | CASP1 (0.50) | CASP1CASP5CASP4HRH4GBA1 | |
| SCHEMBL9689057 | 0.82 | CASP1 (0.50) | CASP1CASP5CASP4HRH4GBA1 | |
| SCHEMBL9689097 | 0.80 | CASP1 (0.58) | CASP1CASP5CASP4HRH4TLR9 | |
| SCHEMBL9688138 | 0.80 | CASP1 (0.58) | CASP1CASP5CASP4HRH4TLR9 | |
| Hydrochloric Acid SCHEMBL9688259 | 0.79 | CASP1 (0.56) | CASP1CASP5CASP4HRH4TLR9 | |
| SCHEMBL9689589 | 0.79 | CASP1 (0.47) | CASP1CASP5CASP4HRH4GBA1 | |
| SCHEMBL9688206 | 0.78 | CASP1 (0.58) | CASP1CASP5CASP4KMT5AMEN1 | |
| SCHEMBL9690413 | 0.77 | CASP1 (0.58) | CASP1CASP5CASP4HRH4GBA1 | |
| SCHEMBL9128566 | 0.77 | CASP1 (0.58) | CASP1CASP5CASP4HRH4GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487510-A1 | Pharmaceutically active amines | THE UPJOHN COMPANY (US) | 1992-05-27 | — | — | EP | disclosed |