Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18115522 | 0.87 | PPARG (0.50) | PPARGPPARAKMT2ASCN9AMRGPRX4 | |
| SCHEMBL29728508 | 0.84 | KMT2A (0.42) | KMT2AMEN1PARP1 | |
| SCHEMBL28781871 | 0.82 | ALDH1A1 (0.44) | KMT2AMEN1MRGPRX4 | |
| SCHEMBL28015642 | 0.82 | CES2 (0.45) | CYP4F2CYP4A11KMT2AMEN1PARP1 | |
| SCHEMBL17294832 | 0.81 | CYP4F2 (0.62) | CYP4F2CYP4A11PPARGPPARAKMT2A | |
| SCHEMBL15546768 | 0.81 | CYP4F2 (0.41) | CYP4F2CYP4A11KMT2AMEN1 | |
| SCHEMBL3643699 | 0.81 | CYP4F2 (0.41) | CYP4F2CYP4A11KMT2AMEN1PARP1 | |
| SCHEMBL16600290 | 0.79 | CYP3A4 (0.44) | KMT2AMEN1 | |
| SCHEMBL9689045 | 0.79 | TDP1 (0.52) | KMT2AMEN1 | |
| SCHEMBL29177417 | 0.79 | MEN1 (0.50) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242060-A | Isoindolinone compounds | 蒙特罗萨医疗公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-102712646-A | RAF inhibitor compounds and methods of use thereof | ARRAY BIOPHARMA INC | 2012-10-03 | — | — | CN | disclosed |
| CN-1946391-A | Combinations comprising alpha-2-delta ligands | PFIZER PROD INC (US) | 2007-04-11 | — | — | CN | disclosed |