Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 10/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10421162 | 1.00 | KMT2A (0.43) | KMT2APOLBLTA4HL3MBTL1NOD1 | |
| SCHEMBL7496434 | 1.00 | KMT2A (0.43) | KMT2APOLBLTA4HL3MBTL1NOD1 | |
| SCHEMBL10421150 | 1.00 | KMT2A (0.43) | KMT2APOLBLTA4HL3MBTL1NOD1 | |
| SCHEMBL9688654 | 1.00 | KMT2A (0.43) | KMT2APOLBLTA4HL3MBTL1NOD1 | |
| SCHEMBL9689026 | 1.00 | KMT2A (0.43) | KMT2APOLBLTA4HL3MBTL1NOD1 | |
| SCHEMBL25481125 | 0.95 | KMT2A (0.42) | KMT2APOLBLTA4HL3MBTL1NOD1 | |
| SCHEMBL23446816 | 0.92 | KMT2A (0.42) | KMT2APOLBLTA4HL3MBTL1NOD1 | |
| SCHEMBL24235742 | 0.89 | KMT2A (0.47) | KMT2APOLBLTA4HL3MBTL1NOD1 | |
| SCHEMBL20492809 | 0.89 | L3MBTL1 (0.42) | KMT2APOLBLTA4HL3MBTL1NOD1 | |
| SCHEMBL23080922 | 0.89 | LTA4H (0.43) | KMT2APOLBLTA4HL3MBTL1NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268377-B1 | GLUTAMIC ACID DERIVATIVES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-03-18 | — | — | EP | disclosed |
| US-4940713-A | ANTITUMOR AGENTS | BURROUGHS WELLCOME CO. (US) | 1990-07-10 | — | — | US | disclosed |
| US-4880812-A | ANTITUMOR AGENTS | BURROUGHS WELLCOME CO. (US) | 1989-11-14 | — | — | US | disclosed |
| EP-0268377-A2 | Glutamic acid derivatives, processes and intermediates for their preparation and pharmaceutical formulations containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-05-25 | — | — | EP | disclosed |