Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MARK3 | P27448 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.42 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690110 | 0.84 | MAPT (0.43) | KDM4EHPGDHSD17B10PIM1GABRA1 | |
| SCHEMBL9691180 | 0.83 | HPGD (0.56) | KDM4EHPGDHSD17B10TSHRNPC1 | |
| SCHEMBL9690839 | 0.81 | HPGD (0.41) | KDM4EHPGDHSD17B10POLBTSHR | |
| SCHEMBL9690969 | 0.79 | KDM4E (0.54) | KDM4EHPGDHSD17B10PIM1GSK3B | |
| SCHEMBL9691113 | 0.78 | HSD11B1 (0.44) | KDM4EHPGDHSD17B10GSK3BGABRA1 | |
| SCHEMBL9691130 | 0.78 | HSD11B1 (0.43) | POLBGABRA1GABRG2GABRB3GABRA2 | |
| SCHEMBL5052559 | 0.78 | BRD4 (0.42) | KDM4EHPGDHSD17B10BRD4ADORA3 | |
| SCHEMBL5061094 | 0.75 | PIM1 (0.40) | KDM4EHPGDHSD17B10BRD4ADORA3 | |
| SCHEMBL5061093 | 0.75 | KDM4E (0.39) | KDM4EHPGDHSD17B10BRD4ADORA3 | |
| SCHEMBL5061095 | 0.75 | KDM4E (0.39) | KDM4EHPGDHSD17B10BRD4ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060843-A | TRIAZOLOPYRIDAZINE DERIVATES | RHONE POULENC AGROCHIMIE (FR) | 1992-05-06 | — | — | CN | disclosed |
| EP-0483027-A2 | Triazolopyridazines, methods for their preparation, their use as herbicides and intermediates | RHONE-POULENC AGROCHIMIE (FR) | 1992-04-29 | — | — | EP | disclosed |