Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | PIM1 | P11309 | 11/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689111 | 0.79 | KDM4E (0.46) | KDM4EHSD17B10PIM1HPGDGABRA1 | |
| SCHEMBL9690110 | 0.75 | MAPT (0.43) | KDM4EHSD17B10PIM1ALDH1A1CYP1A2 | |
| SCHEMBL32664904 | 0.73 | CDK2 (0.63) | KDM4EHSD17B10PIM1ALDH1A1CYP1A2 | |
| SCHEMBL10836184 | 0.73 | KDM4E (0.53) | KDM4EHSD17B10ALDH1A1CYP1A2HPGD | |
| SCHEMBL1665000 | 0.71 | CYP1A2 (0.44) | KDM4EHSD17B10ALDH1A1CYP1A2HPGD | |
| SCHEMBL9691180 | 0.71 | HPGD (0.56) | KDM4EHSD17B10ALDH1A1CYP1A2HPGD | |
| SCHEMBL14077013 | 0.71 | KDM4E (0.55) | KDM4EHSD17B10PIM1ALDH1A1CYP1A2 | |
| SCHEMBL2662898 | 0.70 | PTPN5 (0.62) | KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL11621539 | 0.70 | KDM4E (0.68) | KDM4EHSD17B10PIM1ALDH1A1CYP1A2 | |
| SCHEMBL9689092 | 0.69 | GABRA1 (0.37) | KDM4EHSD17B10ALDH1A1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060843-A | TRIAZOLOPYRIDAZINE DERIVATES | RHONE POULENC AGROCHIMIE (FR) | 1992-05-06 | — | — | CN | disclosed |
| EP-0483027-A2 | Triazolopyridazines, methods for their preparation, their use as herbicides and intermediates | RHONE-POULENC AGROCHIMIE (FR) | 1992-04-29 | — | — | EP | disclosed |