Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5913864 | 0.90 | CA12 (0.51) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL1968355 | 0.88 | CA12 (0.66) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL6987265 | 0.82 | KMT2A (0.57) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL18159264 | 0.82 | MTNR1A (0.50) | MTNR1AMTNR1B | |
| SCHEMBL16416372 | 0.82 | CA12 (0.51) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL21579855 | 0.81 | POLB (0.65) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL9786087 | 0.81 | CA12 (0.50) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL7271744 | 0.81 | CA12 (0.50) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL6678480 | 0.81 | CA1 (0.50) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL10409077 | 0.80 | CYP1A2 (0.56) | KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0189473-B1 | NEW DOPAMINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION, AND THEIR USE AS MEDICINAL PRODUCTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-05-27 | — | — | EP | disclosed |
| US-4958026-A | HYPOTENSIVE AGENTS | SCHERING AKTIENGESLLSCHAFT (DE) | 1990-09-18 | — | — | US | disclosed |
| EP-0189473-A1 | NEW DOPAMINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION, AND THEIR USE AS MEDICINAL PRODUCTS. | SCHERING AG (DE) | 1986-08-06 | — | — | EP | disclosed |
| WO-1986001204-A1 | NEW DOPAMINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION, AND THEIR USE AS MEDICINAL PRODUCTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-02-27 | — | — | WO | disclosed |