Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1968355 | 0.91 | CA12 (0.66) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL21579855 | 0.86 | POLB (0.65) | KMT2ALMNACA12CA1CA2 | |
| SCHEMBL9520757 | 0.85 | NPC1 (0.48) | KMT2ALMNAMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27439284 | 0.84 | CA12 (0.60) | KMT2ALMNACA12CA1CA2 | |
| SCHEMBL5073509 | 0.83 | MTNR1A (0.56) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL16416372 | 0.82 | CA12 (0.51) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL9689182 | 0.82 | CA12 (0.51) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL5913864 | 0.82 | CA12 (0.51) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL9786087 | 0.81 | CA12 (0.50) | LMNACA12CA1CA2CA9 | |
| SCHEMBL7271744 | 0.81 | CA12 (0.50) | KMT2ACA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307193-A1 | AGONISTS OF FOLLICLE STIMULATING HORMONE ACTIVITY | Affymax Research Institute (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002009706-A1 | AGONISTS OF FOLLICLE STIMULATING HORMONE ACTIVITY | SMITHKLINE BEECHAM CORPORATION (US) | 2002-02-07 | — | — | WO | disclosed |