Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9426400 | 0.93 | KMT2A (0.47) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL30366327 | 0.86 | ALDH1A1 (0.39) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL10740378 | 0.84 | ALDH1A1 (0.58) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL16317912 | 0.84 | CYP1A2 (0.43) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL10792423 | 0.82 | NSD2 (0.51) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL10740240 | 0.81 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KDM4E | |
| Diaziquone SCHEMBL4975 | 0.78 | NSD2 (0.59) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KDM4E | |
| Diaziquone SCHEMBL16767645 | 0.75 | NSD2 (0.60) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KMT2A | |
| SCHEMBL3363746 | 0.73 | KMT2A (0.53) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL11767621 | 0.73 | KDM4E (0.70) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493642-A1 | Novel sulfonyl derivatives | Takayanagi, Takeo, Dr. (US) | 1992-07-08 | — | — | EP | claimed |
| EP-0493642-A1 | Novel sulfonyl derivatives | Takayanagi, Takeo, Dr. (US) | 1992-07-08 | — | — | EP | disclosed |