SCHEMBL3363746

SCHEMBL3363746

CCOC(=O)Nc1nc(NC(=O)OCC)nc(NC(=O)OCC)n1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.53
GLA P06280 2/20 0.50
KDM4E B2RXH2 2/20 0.50
POLB P06746 1/20 0.50
ALDH1A1 P00352 6/20 0.49
CYP1A2 P05177 2/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
HPGD P15428 2/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
RECQL P46063 1/20 0.46
NPSR1 Q6W5P4 1/20 0.45
HSD17B10 Q99714 1/20 0.44
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
MGAM O43451 1/20 0.42
GAA P10253 1/20 0.42
SI P14410 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3364492 0.94 KMT2A (0.49) KMT2AGLAKDM4EPOLBALDH1A1
SCHEMBL3367290 0.94 KMT2A (0.49) KMT2AGLAKDM4EPOLBALDH1A1
SCHEMBL6675218 0.87 TSHR (0.56) KMT2AGLAKDM4EALDH1A1CYP1A2
SCHEMBL7906681 0.86 KMT2A (0.46) KMT2AGLAKDM4EPOLBALDH1A1
SCHEMBL11795513 0.85 POLB (0.48) KMT2AGLAKDM4EPOLBALDH1A1
SCHEMBL11704914 0.83 LMNA (0.59) KMT2AKDM4EPOLBALDH1A1SMN1; SMN2
SCHEMBL3365548 0.83 SMN1; SMN2 (0.49) KMT2AGLAKDM4EPOLBALDH1A1
SCHEMBL6682837 0.82 ALOX15 (0.46) KMT2AGLAKDM4EPOLBALDH1A1
SCHEMBL8538892 0.82 CYP1A2 (0.62) KMT2AGLAKDM4EPOLBALDH1A1
SCHEMBL7239923 0.82 ALDH1A1 (0.56) KMT2AGLAKDM4EPOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9556355-B2 Paint compositions, method of paint finishing and painted objects BASF Coating GmbH (DE) 2017-01-31 US disclosed
EP-1440065-B1 METHOD FOR PREPARING ALKOXYCARBONYLAMINO-TRIAZINES BASF SE (DE) 2010-10-06 EP disclosed
EP-1954772-B1 PAINT COMPOSITIONS , METHOD OF PAINT FINISHING AND PAINTED OBJECTS BASF COATINGS JAPAN LTD (JP) 2010-01-20 EP disclosed
US-20090001331-A1 Paint Compositions, a Method of Paint Finishing and Painted Objects BASF COATINGS JAPAN LIMITED (JP) 2009-01-01 US disclosed
EP-1954772-A1 PAINT COMPOSITIONS , METHOD OF PAINT FINISHING AND PAINTED OBJECTS BASF Coatings Japan Ltd. (JP) 2008-08-13 EP disclosed
US-7371856-B2 Preparation of alkoxycarbonylaminotriazines BASF AKTIENGESELLSCHAFT (DE) 2008-05-13 US disclosed
WO-2007063382-A1 PAINT COMPOSITIONS , METHOD OF PAINT FINISHING AND PAINTED OBJECTS BASF COATINGS JAPAN LTD. (DE) 2007-06-07 WO disclosed
US-20070083047-A1 Preparation of Alkoxycarbonylaminotriazines BASF AKTIENGESELLSCHAFT (DE) 2007-04-12 US disclosed
US-7169923-B2 Method for preparing alkoxycarbonylamino-triazines BASF AKTIENGESELLSCHAFT (DE) 2007-01-30 US disclosed
US-20040249149-A1 Method for preparing alkoxycarbonylamino-triazines BASF AKTIENGESELLSCHAFT (DE) 2004-12-09 US disclosed
EP-1087949-A1 PROCESS FOR THE PREPARATION OF TRIAZINE CARBAMATES CYTEC TECHNOLOGY CORP. (US) 2001-04-04 EP disclosed
US-6204381-B1 REACTING A 1,3,5-TRIAZINE DERIVATIVE WITH A (ISO)CYANATE COMPOUND CYTEC TECHNOLOGY CORP. 2001-03-20 US disclosed
WO-1999065883-A1 PROCESS FOR THE PREPARATION OF TRIAZINE CARBAMATES CYTEC TECHNOLOGY CORP. (US) 1999-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040249149-A1 Method for preparing alkoxycarbonylamino-triazines ADH1C, PNMT, TET2 KMT2A 38/4885GLA 1745/4885KDM4E 541/4885
US-20070083047-A1 Preparation of Alkoxycarbonylaminotriazines ADH1C, TET2, PNMT KMT2A 85/4885GLA 2075/4885KDM4E 354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.