Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689398 | 0.84 | TDP1 (0.41) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9689940 | 0.72 | TDP1 (0.40) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9690025 | 0.71 | PPARA (0.42) | KDM4EALDH1A1CA2TDP1TP53 | |
| SCHEMBL9690579 | 0.70 | KDM4E (0.45) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL4762078 | 0.67 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL5031449 | 0.66 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| Hydrochloric Acid SCHEMBL11748562 | 0.66 | KDM4E (0.97) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9689963 | 0.64 | HDAC3 (0.43) | KDM4EALDH1A1HPGDCA2MAPT | |
| SCHEMBL5031507 | 0.64 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL11748555 | 0.64 | KDM4E (0.76) | KDM4EALDH1A1HPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506011-A1 | Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-30 | — | — | EP | disclosed |