Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.48 |
| ▸ | SYK | P43405 | 12/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.45 |
| ▸ | INCENP | Q9NQS7 | 3/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9688368 | 0.99 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1SYKAURKBINCENP | |
| Hydrochloric Acid SCHEMBL9688459 | 0.79 | CYSLTR1 (0.47) | CYSLTR2CYSLTR1CYP1A2 | |
| SCHEMBL8781006 | 0.77 | SYK (0.47) | SYKAURKBINCENPABCB1HTR1A | |
| SCHEMBL9689538 | 0.75 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1ABCB1HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL9689469 | 0.75 | SMN1; SMN2 (0.47) | CYSLTR2CYSLTR1HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL9688361 | 0.74 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1ABCB1HTR1ADRD2 | |
| SCHEMBL9688764 | 0.74 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1CYP1A2 | |
| SCHEMBL8781026 | 0.74 | CYP1A2 (0.47) | SYKAURKBINCENPABCB1HTR1A | |
| SCHEMBL9688234 | 0.74 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1 | |
| SCHEMBL8780987 | 0.73 | CYP1A2 (0.47) | CYSLTR2CYSLTR1SYKAURKBINCENP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0291916-B1 | DITHIOACETAL COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-12 | — | — | EP | disclosed |
| US-5081126-A | QUINOLYL- AND ISOQUINOLYL-METHOXYPHENYL-DITHIOACETYL DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| US-4963576-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS; 5-LIPOXYGENASE INHIBITOR | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0291916-A1 | Dithioacetal compounds, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-23 | — | — | EP | disclosed |