Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688759 | 0.79 | ALOX5 (0.51) | CYSLTR2CYSLTR1ALOX5 | |
| Hydrochloric Acid SCHEMBL9688459 | 0.77 | CYSLTR1 (0.47) | CYSLTR2CYSLTR1CYP1A2ALOX5 | |
| SCHEMBL9688234 | 0.74 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1ALOX5RAB9A | |
| SCHEMBL9689541 | 0.74 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1CYP1A2 | |
| Hydrochloric Acid SCHEMBL9688777 | 0.73 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1ALOX5RAB9A | |
| Hydrochloric Acid SCHEMBL9688368 | 0.73 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1CYP1A2 | |
| SCHEMBL9598981 | 0.71 | RAB9A (0.50) | CYP1A2CYP2A6ALOX5RAB9ACAPN1 | |
| SCHEMBL10434818 | 0.71 | APP (0.60) | CYP1A2CYP2A6ALOX5RAB9A | |
| SCHEMBL9689103 | 0.71 | MAPT (0.41) | CYSLTR2CYSLTR1RAB9ACNR2 | |
| SCHEMBL9689507 | 0.71 | NPC1 (0.58) | CYSLTR2CYSLTR1CYP1A2ALOX5RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0291916-B1 | DITHIOACETAL COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-12 | — | — | EP | disclosed |
| US-5081126-A | QUINOLYL- AND ISOQUINOLYL-METHOXYPHENYL-DITHIOACETYL DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| US-4963576-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS; 5-LIPOXYGENASE INHIBITOR | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0291916-A1 | Dithioacetal compounds, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-23 | — | — | EP | disclosed |