Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CTH | P32929 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 5/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | APEX1 | P27695 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2902587 | 0.95 | — | — | |
| Glycine SCHEMBL9555848 | 0.86 | GLRA1 (0.46) | TSHRCTHALDH1A1EGLN1ITGB1 | |
| SCHEMBL3379485 | 0.80 | ALDH1A1 (0.38) | CTHALDH1A1EGLN1ITGB1ITGA5 | |
| SCHEMBL10067714 | 0.79 | EGLN1 (0.41) | CTHALDH1A1EGLN1ITGB1ITGA5 | |
| SCHEMBL14369161 | 0.78 | MCL1 (0.41) | ALDH1A1LMNAFAAHMEN1KMT2A | |
| SCHEMBL11115141 | 0.78 | MAOA (0.30) | — | |
| SCHEMBL4804241 | 0.77 | ALDH1A1 (0.39) | CTHALDH1A1EGLN1ITGB1ITGA5 | |
| SCHEMBL4804250 | 0.77 | PTPN1 (0.40) | CTHALDH1A1EGLN1ITGB1ITGA5 | |
| SCHEMBL3382017 | 0.77 | ALDH1A1 (0.39) | CTHALDH1A1EGLN1ITGB1ITGA5 | |
| SCHEMBL2807522 | 0.75 | EGLN1 (0.46) | CTHALDH1A1EGLN1ITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089388-A | Conjugates of a salicyclic acid derivative and a polypeptide or enzyme for sensitive immunoassays to monitor serum aspirin concentration | SYNTEX (U.S.A.) INC. (US) | 1992-02-18 | — | — | US | disclosed |