Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | ACR | P10323 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689823 | 0.87 | EPHX2 (0.56) | F9PRSS1ACREPHX2TRPV1 | |
| SCHEMBL27690177 | 0.83 | PARP10 (0.50) | PRSS1ACRNPC1RAB9AMEN1 | |
| SCHEMBL7336070 | 0.81 | MLYCD (0.52) | F9NPC1RAB9ATRPV1MEN1 | |
| SCHEMBL9235738 | 0.81 | PRSS1 (0.45) | PRSS1ACRNPC1RAB9AMEN1 | |
| SCHEMBL4104661 | 0.81 | KMT2A (0.59) | PRSS1ACREPHX2MEN1KMT2A | |
| SCHEMBL27671251 | 0.81 | PRSS1 (0.62) | PRSS1ACRNPC1RAB9AMEN1 | |
| SCHEMBL9689740 | 0.81 | RXRA (0.43) | F9PRSS1ACREPHX2NPC1 | |
| SCHEMBL9688343 | 0.81 | POLB (0.43) | PRSS1ACREPHX2RAB9AMEN1 | |
| SCHEMBL22416610 | 0.80 | PRSS1 (0.48) | PRSS1ACRNPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL29825181 | 0.80 | KMT2A (0.57) | PRSS1ACREPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486702-A1 | PHENYL 4-GUANIDINOBENZOATE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND PROTEASE INHIBITOR CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-05-27 | — | — | EP | disclosed |