Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690787 | 0.88 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTRAB9AGAA | |
| SCHEMBL9692020 | 0.87 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTRAB9AGAA | |
| SCHEMBL9839402 | 0.87 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTRAB9AGAA | |
| SCHEMBL11008151 | 0.86 | ALDH1A1 (0.74) | ALDH1A1KDM4EMAPTGAACACNA1C | |
| SCHEMBL10648966 | 0.86 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTRAB9AGAA | |
| SCHEMBL9689489 | 0.85 | KDM4E (0.53) | ALDH1A1KDM4ECACNA1CCACNA1FCACNA1D | |
| SCHEMBL9691638 | 0.85 | KDM4E (0.55) | ALDH1A1KDM4EMAPTRAB9AGAA | |
| SCHEMBL9691494 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTRAB9AGAA | |
| SCHEMBL9690702 | 0.84 | KDM4E (0.53) | ALDH1A1KDM4EMAPTRAB9AGAA | |
| SCHEMBL9690867 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTRAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071819-B2 | DIHYDROPYRIDINES WITH A POSITIVE INOTROPIC ACTIVITY, THEIR USE IN PHARMACEUTICAL PREPARATIONS, AND PROCESSES FOR THEIR PREPARATION | BAYER AG (DE) | 1992-06-10 | — | — | EP | disclosed |
| EP-0071819-B1 | DIHYDROPYRIDINES WITH A POSITIVE INOTROPIC ACTIVITY, THEIR USE IN PHARMACEUTICAL PREPARATIONS, AND PROCESSES FOR THEIR PREPARATION | BAYER AG (DE) | 1987-04-22 | — | — | EP | disclosed |
| EP-0071819-A1 | Dihydropyridines with a positive inotropic activity, their use in pharmaceutical preparations, and processes for their preparation | BAYER AG (DE) | 1983-02-16 | — | — | EP | disclosed |