Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10641540 | 1.00 | SLC6A5 (0.48) | SLC6A5PAOXHDAC6MAOAMAOB | |
| Hydrochloric Acid SCHEMBL10642172 | 0.99 | SLC6A5 (0.49) | SLC6A5PAOXHDAC6MAOAMAOB | |
| SCHEMBL11015199 | 0.93 | PAOX (0.51) | SLC6A5PAOXHDAC6MAOAMAOB | |
| SCHEMBL11011464 | 0.93 | PAOX (0.51) | SLC6A5PAOXHDAC6MAOAMAOB | |
| SCHEMBL11009412 | 0.91 | PAOX (0.50) | SLC6A5PAOXHDAC6MAOAMAOB | |
| SCHEMBL10641835 | 0.91 | PAOX (0.50) | SLC6A5PAOXHDAC6MAOAMAOB | |
| SCHEMBL524729 | 0.87 | MAOA (0.44) | SLC6A5PAOXHDAC6MAOAMAOB | |
| SCHEMBL524298 | 0.87 | MAOA (0.44) | SLC6A5PAOXHDAC6MAOAMAOB | |
| SCHEMBL524786 | 0.85 | PAOX (0.47) | PAOXHDAC6MAOAMAOBCA12 | |
| SCHEMBL525137 | 0.85 | PAOX (0.47) | PAOXHDAC6MAOAMAOBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4529549-A | Compound containing guanidine and amino groups | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1985-07-16 | — | — | US | claimed |
| JP-59042356-A | — | — | None | — | — | JP | disclosed |
| WO-2010028389-A1 | IMAGE-GUIDED ENERGY DEPOSITION FOR TARGETED DRUG DELIVERY | THE METHODIST HOSPITAL RESEARCH INSTITUTE (US) | 2010-03-11 | — | — | WO | disclosed |
| EP-0181592-B1 | USE OF SPERGUALIN DERIVATIVES FOR THE PREPARATION OF MEDICAMENTS HAVING IMMUNOSUPPRESSIVE ACTIVITY | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-4851446-A | SPERGUALIN-LIKE GUANIDINES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0105193-B1 | SPERGUALIN-RELATED COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1988-08-24 | — | — | EP | disclosed |
| EP-0181592-A2 | Use of spergualin derivatives for the preparation of medicaments having immunosuppressive activity | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1986-05-21 | — | — | EP | disclosed |
| US-4529549-A | Compound containing guanidine and amino groups | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1985-07-16 | — | — | US | disclosed |
| EP-0105193-A2 | Spergualin-related compounds, processes for the preparation thereof and their use as medicaments | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1984-04-11 | — | — | EP | disclosed |
| JP-S5942356-A | SPERGUALIN-RELATED COMPOUND AND PREPARATION THEREOF | MICROBIAL CHEM RES FOUND | 1984-03-08 | — | — | JP | disclosed |