Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 2/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690051 | 1.00 | MAPT (0.34) | MAPTKDM4EMEN1LMNAHTT | |
| SCHEMBL9661588 | 0.77 | NPC1 (0.44) | MAPTKDM4EMEN1LMNAHTT | |
| SCHEMBL9661581 | 0.77 | NPC1 (0.44) | MAPTKDM4EMEN1LMNAHTT | |
| SCHEMBL9690654 | 0.75 | MAPT (0.55) | MAPTKDM4EMEN1LMNAHTT | |
| SCHEMBL9690661 | 0.75 | MAPT (0.55) | MAPTKDM4EMEN1LMNAHTT | |
| SCHEMBL9658750 | 0.73 | KDM4E (0.42) | MAPTKDM4EMEN1LMNAHTT | |
| SCHEMBL9658754 | 0.73 | KDM4E (0.42) | MAPTKDM4EMEN1LMNAHTT | |
| SCHEMBL9690044 | 0.73 | KMT2A (0.43) | MAPTKDM4EMEN1LMNAHTT | |
| SCHEMBL9658741 | 0.73 | NPC1 (0.36) | MAPTKDM4EMEN1LMNAHTT | |
| SCHEMBL9690040 | 0.73 | KMT2A (0.43) | MAPTKDM4EMEN1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520275-A2 | 2-(3-Substituted phenylhydrazino)-2-thiazoline and 2-(3-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |