Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 2/20 | 0.44 |
| ▸ | DNTT | P04053 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9692233 | 0.93 | POLA1 (0.37) | POLA1DNTTPOLBEPHX1TSHR | |
| SCHEMBL9692238 | 0.78 | ALDH1A1 (0.37) | POLBRAB9A | |
| SCHEMBL9692186 | 0.73 | PPM1B (0.32) | — | |
| SCHEMBL14967185 | 0.72 | NAAA (0.44) | EPHX1TSHRPRKCA | |
| SCHEMBL12358905 | 0.71 | POLA1 (0.41) | POLA1DNTTPOLBTSHRHTT | |
| SCHEMBL9692383 | 0.71 | HTT (0.43) | POLA1DNTTPOLBHTT | |
| SCHEMBL9691800 | 0.71 | HTT (0.43) | POLA1DNTTPOLBHTT | |
| SCHEMBL14967084 | 0.70 | NAAA (0.42) | EPHX1TSHRPRKCA | |
| SCHEMBL28024539 | 0.69 | SPHK1 (0.35) | — | |
| SCHEMBL9692162 | 0.69 | ABCB1 (0.35) | SMN1; SMN2PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153692-B1 | METHOD FOR ISOMERIZATION A GLYCIDATE DERIVATIVE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-4621150-A | METAL PERHALATE OR SULFONATE OR COMPLEX; GLYCIDATE, 2-HYDROXY-3-BUTENOATE, EPOXIDE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-11-04 | — | — | US | disclosed |
| EP-0153692-A2 | Method for isomerization a glycidate derivative | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1985-09-04 | — | — | EP | disclosed |