Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.62 |
| ▸ | LTA4H | P09960 | 4/20 | 0.58 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689109 | 0.98 | NR5A1 (0.66) | NR5A1LTA4HDRD4DRD2DRD3 | |
| SCHEMBL2470706 | 0.89 | NR5A1 (0.75) | NR5A1LTA4HDRD4DRD2DRD3 | |
| SCHEMBL19513829 | 0.86 | LTA4H (0.55) | NR5A1LTA4HDRD4DRD2DRD3 | |
| SCHEMBL9128116 | 0.86 | NR5A1 (0.79) | NR5A1LTA4HDRD4DRD2DRD3 | |
| SCHEMBL11230467 | 0.86 | NR5A1 (0.79) | NR5A1LTA4HDRD4DRD2DRD3 | |
| SCHEMBL16902828 | 0.86 | NR5A1 (0.79) | NR5A1LTA4HDRD4DRD2DRD3 | |
| SCHEMBL6858863 | 0.86 | NR5A1 (0.79) | NR5A1LTA4HDRD4DRD2DRD3 | |
| SCHEMBL11615156 | 0.86 | KCNA3 (0.52) | NR5A1LTA4HDRD3SLC6A2SLC6A3 | |
| SCHEMBL1129755 | 0.86 | NR5A1 (0.79) | NR5A1LTA4HDRD4DRD2DRD3 | |
| SCHEMBL8571102 | 0.86 | NR5A1 (0.79) | NR5A1LTA4HDRD4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120843-A | Nervous system disorders | UPJOHN (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0487510-A1 | Pharmaceutically active amines | THE UPJOHN COMPANY (US) | 1992-05-27 | — | — | EP | disclosed |
| EP-0358676-A1 | PHARMACEUTICALLY ACTIVE AMINES | THE UPJOHN COMPANY (US) | 1990-03-21 | — | — | EP | disclosed |
| EP-0293078-A1 | Pharmaceutically active amines | THE UPJOHN COMPANY (US) | 1988-11-30 | — | — | EP | disclosed |
| WO-1988008424-A1 | PHARMACEUTICALLY ACTIVE AMINES | THE UPJOHN COMPANY (US) | 1988-11-03 | — | — | WO | disclosed |