Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | MTOR | P42345 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.62 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.62 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.62 |
| ▸ | GMNN | O75496 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.62 |
| ▸ | THPO | P40225 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | HBB | P68871 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CDA | P32320 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690202 | 1.00 | LMNA (0.62) | LMNAMTORALDH1A1TP53THRB | |
| SCHEMBL1138566 | 0.87 | LMNA (0.64) | LMNAMTORALDH1A1TP53THRB | |
| SCHEMBL1138565 | 0.87 | LMNA (0.64) | LMNAMTORALDH1A1TP53THRB | |
| SCHEMBL1138717 | 0.86 | LMNA (0.63) | LMNAMTORALDH1A1TP53THRB | |
| SCHEMBL1138719 | 0.86 | LMNA (0.63) | LMNAMTORALDH1A1TP53THRB | |
| SCHEMBL18858919 | 0.85 | LMNA (0.62) | LMNAMTORALDH1A1TP53THRB | |
| SCHEMBL2584289 | 0.85 | LMNA (0.62) | LMNAMTORALDH1A1TP53THRB | |
| SCHEMBL6297856 | 0.85 | LMNA (0.62) | LMNAMTORALDH1A1TP53THRB | |
| SCHEMBL21423108 | 0.85 | LMNA (0.62) | LMNAMTORALDH1A1TP53THRB | |
| SCHEMBL5697581 | 0.85 | LMNA (0.62) | LMNAMTORALDH1A1TP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992003127-A1 | COMPOSITIONS AND METHODS FOR TREATING HIV INFECTIONS | RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) | 1992-03-05 | — | — | WO | claimed |
| WO-1992003127-A1 | COMPOSITIONS AND METHODS FOR TREATING HIV INFECTIONS | RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) | 1992-03-05 | — | — | WO | disclosed |
| US-4749647-A | Polymerization-induced separation assay using recognition pairs | GENETIC SYSTEMS CORPORATION (US) | 1988-06-07 | — | — | US | disclosed |