Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.45 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20081129 | 0.93 | ACE (0.53) | ACEFOLH1RIMKLANAALAD2NOD1 | |
| SCHEMBL24945914 | 0.93 | ACE (0.53) | ACEFOLH1RIMKLANAALAD2NOD1 | |
| SCHEMBL2306568 | 0.90 | CTSK (0.47) | FOLH1KLK5PPARGPPARACTSS | |
| SCHEMBL2398972 | 0.90 | CTSK (0.47) | FOLH1KLK5PPARGPPARACTSS | |
| SCHEMBL6409351 | 0.90 | CTSK (0.47) | FOLH1KLK5PPARGPPARACTSS | |
| SCHEMBL16350093 | 0.88 | ACE (0.49) | ACEFOLH1RIMKLANAALAD2NOD1 | |
| SCHEMBL2769978 | 0.87 | FOLH1 (0.56) | ACEFOLH1RIMKLANAALAD2PPARG | |
| SCHEMBL1324835 | 0.87 | FOLH1 (0.56) | ACEFOLH1RIMKLANAALAD2PPARG | |
| SCHEMBL1318658 | 0.87 | FOLH1 (0.56) | ACEFOLH1RIMKLANAALAD2PPARG | |
| SCHEMBL863895 | 0.83 | CTSK (0.48) | FOLH1RIMKLANAALAD2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492316-A1 | Condensed heterocyclic oligoglutamate derivatives, their production and pharmaceutical compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1992-07-01 | — | — | EP | disclosed |