SCHEMBL1324835

SCHEMBL1324835

CC(C)(C)OC(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 11/20 0.56
NAALAD2 Q9Y3Q0 2/20 0.56
RIMKLA Q8IXN7 1/20 0.56
PPARG P37231 1/20 0.49
PPARA Q07869 1/20 0.49
CTSS P25774 2/20 0.49
CTSK P43235 2/20 0.49
ACE P12821 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1318658 1.00 FOLH1 (0.56) FOLH1NAALAD2RIMKLAPPARGPPARA
SCHEMBL2769978 1.00 FOLH1 (0.56) FOLH1NAALAD2RIMKLAPPARGPPARA
SCHEMBL24945914 0.94 ACE (0.53) FOLH1NAALAD2RIMKLAPPARGPPARA
SCHEMBL8215506 0.94 CTSS (0.51) FOLH1NAALAD2RIMKLAPPARGPPARA
SCHEMBL20081129 0.94 ACE (0.53) FOLH1NAALAD2RIMKLAPPARGPPARA
Glutamic Acid SCHEMBL2482358 0.91 GRM8 (0.51) FOLH1NAALAD2RIMKLAPPARGPPARA
SCHEMBL30853504 0.91 PPARA (0.48) FOLH1NAALAD2RIMKLAPPARGPPARA
SCHEMBL3432850 0.90 CTSK (0.51) FOLH1NAALAD2RIMKLAPPARGPPARA
SCHEMBL6036315 0.90 CTSK (0.51) FOLH1NAALAD2RIMKLAPPARGPPARA
SCHEMBL3431559 0.90 CTSK (0.51) FOLH1NAALAD2RIMKLAPPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 808 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12377110-B2 Fospropofol methods and compositions EPALEX CORPORATION (US) 2025-08-05 US claimed
CN-119798062-A Method for catalyzing quinone hydroxylation reaction of alkene by iron 南京师范大学 2025-04-11 CN claimed
CN-119798139-A Method for synthesizing phenolic compound by iron-catalyzed hydroxylation reaction of aromatic compound 南京师范大学 2025-04-11 CN claimed
CN-119798083-A Iron-catalyzed aromatic compound carbon-hydrogen bond hydroxylation nitration method 南京师范大学 2025-04-11 CN claimed
CN-119775348-A Preparation method of polypeptide Angstrom Pi Dalong acetate 深圳市第二人民医院(深圳市转化医学研究院) 2025-04-08 CN claimed
CN-119751853-A Aqueous phase green preparation method and application of polyester microspheres 青岛科技大学 2025-04-04 CN claimed
CN-119591663-A Targeting cell surface glycoprotein interaction cross-linking agent and preparation method thereof 辽宁师范大学 2025-03-11 CN claimed
CN-116199572-B Method for alpha-bromination of iron-catalyzed ketone 南京师范大学 2025-01-14 CN claimed
CN-119303634-A Preparation method of nickel-based gel-carbon nitride composite photocatalyst and application of nickel-based gel-carbon nitride composite photocatalyst in CO2Application in reduction 河北大学 2025-01-14 CN claimed
CN-115925544-B Method for ring-opening acrylation of tertiary alcohol through iron catalytic oxidation 南京师范大学 2025-01-14 CN claimed
WO-2012150220-A1 RADIOLABELED AMINO ACIDS FOR DIAGNOSTIC IMAGING BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2012-11-08 WO claimed
CN-101538242-B Synthetic method of Benazepril key intermediate S-amino substance UNIV ZHEJIANG TECHNOLOGY 2011-05-25 CN claimed
CN-100590068-C Method for preparing primary amine carbon nano tube UNIV TONGJI 2010-02-17 CN claimed
CN-101538242-A Synthetic method of Benazepril key intermediate S-amino substance UNIV ZHEJIANG TECHNOLOGY 2009-09-23 CN claimed
EP-1542976-B1 SUBSTITUTED 4-(INDAZOL-3-YL)PHENOLS AS ESTROGEN RECEPTOR (ER) LIGANDS AND THEIR USE IN THE TREATMENT OF INFLAMMATORY DISEASES WYETH CORP (US) 2009-02-04 EP claimed
CN-101177259-A Method for preparing primary amine carbon nano tube UNIV TONGJI (CN) 2008-05-14 CN claimed
US-6387890-B1 CARDIOVASCULAR DISORDERS; GASTROINTESTINAL DISORDERS; SEXUAL DISORDERS TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2002-05-14 US claimed
EP-1049660-A1 COMPOSITIONS AND METHODS FOR INHIBITING ARGINASE ACTIVITY THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2000-11-08 EP claimed
WO-1999019295-A1 COMPOSITIONS AND METHODS FOR INHIBITING ARGINASE ACTIVITY TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1999-04-22 WO claimed
US-4824974-A Synthesis for the preparation of 4-amino-4,5-dihydro-2-furancarboxylic acid MERRELL DOW PHARMACEUTICALS INC. (US) 1989-04-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12377110-B2 Fospropofol methods and compositions FOS, FOSB, PFAS FOLH1 387/4885NAALAD2 4066/4885RIMKLA 1929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.