Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NNMT | P40261 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668728 | 0.86 | MAPT (0.47) | TDP1POLBCYP1A2MAPTSMN1; SMN2 | |
| SCHEMBL23145042 | 0.82 | KMT2A (0.44) | KMT2AMEN1MAPTGAASMN1; SMN2 | |
| SCHEMBL29843352 | 0.82 | KMT2A (0.44) | KMT2AMEN1MAPTGAASMN1; SMN2 | |
| SCHEMBL2420837 | 0.80 | KMT2A (0.40) | TDP1KMT2ACYP1A2MEN1MAPT | |
| SCHEMBL1902321 | 0.78 | KDM4E (0.44) | TDP1KMT2AMEN1MAPTLDHA | |
| SCHEMBL25238882 | 0.77 | CYP1A2 (0.41) | TDP1POLBKMT2ANNMTCYP1A2 | |
| SCHEMBL5726874 | 0.77 | TDP1 (0.50) | TDP1POLBKMT2ANNMTPRKAG1 | |
| SCHEMBL25236718 | 0.74 | ERN1 (0.44) | MAPTMAPK1GFERERN1 | |
| SCHEMBL29206031 | 0.74 | ALDH1A1 (0.42) | TDP1POLBKMT2ANNMTCYP1A2 | |
| SCHEMBL30449338 | 0.74 | ERN1 (0.44) | MAPTMAPK1GFERERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298134-B1 | AROMATIC HETEROCYCLIC CARBOXYLIC ACID AMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 1992-11-11 | — | — | EP | disclosed |
| US-4965266-A | Antiallergens | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1990-10-23 | — | — | US | disclosed |
| EP-0298134-A1 | AROMATIC HETEROCYCLIC CARBOXYLIC ACID AMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-01-11 | — | — | EP | disclosed |