Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 4/20 | 0.47 |
| ▸ | GABRD | O14764 | 4/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.47 |
| ▸ | GABRE | P78334 | 4/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.47 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.47 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10747046 | 0.86 | MEN1 (0.46) | KDM4EMEN1KMT2AGABRPGABRD | |
| SCHEMBL400611 | 0.75 | RCE1 (0.55) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL28826053 | 0.75 | KDM4E (0.49) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9690375 | 0.74 | GABRP (0.51) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9689767 | 0.73 | GABRP (0.59) | KDM4EMEN1KMT2AGABRPGABRD | |
| SCHEMBL2218077 | 0.72 | KDM4E (0.49) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9688866 | 0.72 | GABRP (0.76) | MEN1KMT2AGABRPGABRDGABRA1 | |
| SCHEMBL9688746 | 0.72 | GABRP (0.58) | KDM4EMEN1KMT2AGABRPGABRD | |
| Bicarbonate SCHEMBL9678990 | 0.71 | GPR3 (0.76) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9690925 | 0.70 | GABRP (0.78) | KDM4EMEN1KMT2AGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249301-B1 | Pyrido[2,3-b]indoles | BEECHAM GROUP PLC (GB) | 1992-05-27 | — | — | EP | claimed |