Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9581167 | 0.78 | ALDH1A1 (0.55) | RAB9ANPC1SMN1; SMN2TP53GAA | |
| SCHEMBL9690709 | 0.78 | POLB (0.50) | RAB9ANPC1SMN1; SMN2TP53KMT2A | |
| SCHEMBL9690723 | 0.78 | POLB (0.50) | RAB9ANPC1SMN1; SMN2TP53KMT2A | |
| SCHEMBL8326648 | 0.78 | KMT2A (0.60) | RAB9ANPC1SMN1; SMN2TP53KMT2A | |
| SCHEMBL9690774 | 0.77 | POLB (0.46) | RAB9ANPC1SMN1; SMN2TP53GAA | |
| SCHEMBL9658772 | 0.76 | POLB (0.70) | RAB9ANPC1SMN1; SMN2TP53GAA | |
| SCHEMBL9689454 | 0.75 | POLB (0.44) | RAB9ANPC1SMN1; SMN2TP53KMT2A | |
| Hydrochloric Acid SCHEMBL11749763 | 0.75 | POLB (0.68) | RAB9ANPC1SMN1; SMN2TP53GAA | |
| SCHEMBL9690030 | 0.74 | NPC1 (0.47) | RAB9ANPC1SMN1; SMN2TP53GAA | |
| SCHEMBL11751742 | 0.74 | GAA (0.55) | RAB9ANPC1SMN1; SMN2TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520275-A2 | 2-(3-Substituted phenylhydrazino)-2-thiazoline and 2-(3-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |