Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043111 | 1.00 | KDM4E (0.40) | KDM4EKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9043198 | 1.00 | KDM4E (0.40) | KDM4EKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL192403 | 0.83 | MAOB (0.50) | KDM4EKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL193277 | 0.82 | KDM4E (0.44) | KDM4EKMT2ASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL9042229 | 0.77 | LMNA (0.46) | KMT2AALDH1A1LMNA | |
| SCHEMBL4689225 | 0.77 | LMNA (0.46) | KMT2AALDH1A1LMNA | |
| SCHEMBL9042525 | 0.77 | CACNA1B (0.51) | KDM4EKMT2ASMN1; SMN2ALDH1A1CACNA1B | |
| SCHEMBL9043043 | 0.77 | CACNA1B (0.51) | KDM4EKMT2ASMN1; SMN2ALDH1A1CACNA1B | |
| SCHEMBL3379309 | 0.75 | SMN1; SMN2 (0.41) | KMT2ASMN1; SMN2ALDH1A1MEN1HPGD | |
| SCHEMBL2574959 | 0.74 | LTA4H (0.49) | KDM4EKMT2ASMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512352-A2 | Substituted carboxylic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-11-11 | — | — | EP | disclosed |