Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9691841 | 0.80 | KDM4E (0.45) | MALT1KDM4EALDH1A1MAPTDRD2 | |
| SCHEMBL9692276 | 0.79 | MALT1 (0.48) | MALT1TP53 | |
| SCHEMBL9240649 | 0.75 | MALT1 (0.48) | MALT1MEN1KMT2ATP53 | |
| SCHEMBL9690387 | 0.72 | MALT1 (0.42) | MALT1DRD2MEN1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL9242623 | 0.72 | TP53 (0.44) | MALT1ALDH1A1TP53 | |
| SCHEMBL8301033 | 0.71 | NAMPT (0.49) | ALDH1A1ALOX5NAMPTNOTUM | |
| SCHEMBL9690389 | 0.69 | MALT1 (0.48) | MALT1ALOX5DRD2TP53 | |
| SCHEMBL9690310 | 0.69 | ALDH1A1 (0.49) | KDM4EALDH1A1DRD2L3MBTL1KMT2A | |
| SCHEMBL17443379 | 0.69 | TP53 (0.55) | MAPTTP53 | |
| SCHEMBL9425674 | 0.69 | MAPT (0.44) | MALT1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112855-A | Nootropic Agents | CIBA-GEIGY CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |
| US-4957928-A | NOOTROPIC AGENTS, COGNITION ACTIVATORS | CIBA-GEIGY CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |