Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10531104 | 0.91 | NOTUM (0.48) | NAMPTCYP4F2CYP4A11NOTUMALDH1A1 | |
| SCHEMBL2246761 | 0.81 | GAA (0.47) | CYP4F2CYP4A11NOTUMALDH1A1GAA | |
| SCHEMBL24651033 | 0.78 | NAMPT (0.52) | NAMPTCYP4F2CYP4A11NOTUMALDH1A1 | |
| SCHEMBL3901891 | 0.77 | ALDH1A1 (0.46) | CYP4F2CYP4A11ALDH1A1SMN1; SMN2ALOX5 | |
| SCHEMBL24650862 | 0.77 | NAMPT (0.43) | NAMPTCYP4F2CYP4A11NOTUMALDH1A1 | |
| SCHEMBL8291564 | 0.77 | IDO1 (0.49) | IDO1PREP | |
| SCHEMBL7220703 | 0.77 | MAPT (0.46) | ALDH1A1SMN1; SMN2TDP1IDO1PREP | |
| SCHEMBL29466624 | 0.76 | TSHR (0.46) | NAMPTCYP4F2CYP4A11NOTUMALDH1A1 | |
| SCHEMBL8922456 | 0.75 | MTNR1A (0.54) | NAMPTCYP4F2CYP4A11NOTUMALDH1A1 | |
| SCHEMBL8643065 | 0.75 | SIGMAR1 (0.46) | NOTUMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661273-B1 | Indane derivatives and processes for preparing the same | TANABE SEIYAKU CO (JP) | 1999-05-19 | — | — | EP | disclosed |
| US-5686452-A | PROTECTING FROM ENDOTOXIN SHOCK; TREATMENT OF NEPHRITIS | TANABE SEIYAKU CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0661273-A1 | Indane derivative and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |