Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.53 |
| ▸ | MAOB | P27338 | 8/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032358 | 0.79 | ADORA2A (0.56) | ADORA2BADORA2AKMT2AALDH1A1ADORA3 | |
| SCHEMBL9031659 | 0.77 | PDE4A (0.54) | ADORA2BADORA2A | |
| SCHEMBL9031509 | 0.76 | ADORA2A (0.47) | ADORA2BADORA2AKMT2AALDH1A1ADORA3 | |
| SCHEMBL9032044 | 0.73 | PDE4A (0.56) | ADORA2BADORA2AHPGDADORA3 | |
| SCHEMBL9030631 | 0.73 | ADORA2B (0.46) | ADORA2BADORA2AHIF1AKMT2AALDH1A1 | |
| SCHEMBL1946830 | 0.72 | ADORA2B (0.62) | ADORA2BADORA2AHPGDALDH1A1ADORA3 | |
| SCHEMBL9030428 | 0.72 | ADORA2A (0.52) | ADORA2BADORA2AHPGDALDH1A1 | |
| SCHEMBL9030681 | 0.71 | HPGD (0.51) | ADORA2BHIF1AHPGDKMT2AALDH1A1 | |
| SCHEMBL9031302 | 0.71 | ADORA2A (0.54) | ADORA2BADORA2A | |
| SCHEMBL9031357 | 0.70 | PDE4A (0.53) | ADORA2BADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173492-A | Bronchodilator agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-12-22 | — | — | US | disclosed |