Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PDE1A | P54750 | 2/20 | 0.45 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.45 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CNOT7 | Q9UIV1 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029960 | 0.89 | PDE4A (0.54) | ADORA2BPDE1APDE1BPDE1CPDE4A | |
| SCHEMBL9031659 | 0.85 | PDE4A (0.54) | ADORA2BPDE1APDE1BPDE1CPDE4A | |
| SCHEMBL9031357 | 0.83 | PDE4A (0.53) | ADORA2BPDE1APDE1BPDE1CPDE4A | |
| SCHEMBL9032358 | 0.81 | ADORA2A (0.56) | ADORA2BALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL9030681 | 0.78 | HPGD (0.51) | ADORA2BSMN1; SMN2RXFP1PDE1APDE1B | |
| SCHEMBL1944712 | 0.77 | POLB (0.70) | ADORA2BSMN1; SMN2RXFP1PDE1APDE1B | |
| SCHEMBL9031072 | 0.74 | PDE4A (0.50) | ADORA2BSMN1; SMN2PDE1APDE1BPDE1C | |
| SCHEMBL9031011 | 0.74 | ADORA2A (0.52) | ADORA2BALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL9031302 | 0.73 | ADORA2A (0.54) | ADORA2BPDE1APDE1BPDE1CPDE4A | |
| SCHEMBL9692126 | 0.73 | MAOA (0.53) | ADORA2BHIF1AALDH1A1KMT2AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417790-B1 | S-triazolo[3,4-i]purine derivatives | KYOWA HAKKO KOGYO KK (JP) | 1996-12-04 | — | — | EP | claimed |
| US-5173492-A | Bronchodilator agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-12-22 | — | — | US | claimed |
| EP-0417790-A2 | S-triazolo[3,4-i]purine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-03-20 | — | — | EP | claimed |
| EP-0417790-B1 | S-triazolo[3,4-i]purine derivatives | KYOWA HAKKO KOGYO KK (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5173492-A | Bronchodilator agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-12-22 | — | — | US | disclosed |
| EP-0417790-A2 | S-triazolo[3,4-i]purine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-03-20 | — | — | EP | disclosed |