Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 10/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.56 |
| ▸ | RELA | Q04206 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25319871 | 0.85 | RAB9A (0.68) | RAB9ASMN1; SMN2TP53NPC1PKM | |
| SCHEMBL25319814 | 0.84 | RAB9A (0.64) | RAB9ASMN1; SMN2TP53NPC1PKM | |
| SCHEMBL25317747 | 0.84 | RAB9A (0.82) | RAB9ASMN1; SMN2TP53NPC1PKM | |
| SCHEMBL25320555 | 0.83 | RAB9A (0.80) | RAB9ASMN1; SMN2TP53NPC1PKM | |
| SCHEMBL25321130 | 0.82 | RAB9A (0.62) | RAB9ASMN1; SMN2TP53NPC1PKM | |
| SCHEMBL9692985 | 0.82 | RAB9A (0.60) | RAB9ASMN1; SMN2TP53NPC1PKM | |
| SCHEMBL25321220 | 0.80 | RAB9A (0.80) | RAB9ASMN1; SMN2TP53NPC1PKM | |
| SCHEMBL9690532 | 0.80 | RAB9A (0.70) | RAB9ASMN1; SMN2TP53NPC1PKM | |
| SCHEMBL25317194 | 0.80 | RAB9A (0.56) | RAB9ASMN1; SMN2TP53NPC1PKM | |
| SCHEMBL25319204 | 0.79 | RAB9A (0.62) | RAB9ASMN1; SMN2TP53NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081253-A | IMIDAZO(4,5-C)PYRIDINES AS ANTIOSTEOPOROTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-01-14 | — | — | US | disclosed |
| EP-0434405-A1 | Imidazo[4,5-c]pyridines as antiosteoporotic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-06-26 | — | — | EP | disclosed |