Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.56 |
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TOP2A | P11388 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25321130 | 0.88 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL9692083 | 0.87 | RAB9A (0.60) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL9692576 | 0.85 | RAB9A (0.60) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL25319871 | 0.85 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL31325540 | 0.83 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL25321220 | 0.83 | RAB9A (0.80) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL25320555 | 0.83 | RAB9A (0.80) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL9690532 | 0.82 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL9693023 | 0.80 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL9692137 | 0.80 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2PKMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137885-A1 | COMPOUND HAVING PYRIDOIMIDAZOLE AS PARENT NUCLEUS, AND PREPARATION METHOD FOR AND USE OF COMPOUND | 中国药科大学 | 2023-07-27 | — | — | WO | disclosed |