Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.57 |
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | HK1 | P19367 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9692136 | 1.00 | MAPT (0.57) | MAPTMEN1KMT2ALMNAGSK3B | |
| SCHEMBL10757983 | 0.79 | MAPT (0.56) | MAPTMEN1KMT2ALMNAGSK3B | |
| SCHEMBL10757993 | 0.79 | MAPT (0.56) | MAPTMEN1KMT2ALMNAGSK3B | |
| SCHEMBL10656043 | 0.78 | POLB (0.44) | MAPTMEN1KMT2ALMNAGSK3B | |
| SCHEMBL10656030 | 0.77 | MAPT (0.45) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL10758203 | 0.77 | POLB (0.66) | MAPTMEN1KMT2ALMNAGSK3B | |
| SCHEMBL10758207 | 0.77 | POLB (0.66) | MAPTMEN1KMT2ALMNAGSK3B | |
| SCHEMBL9694281 | 0.76 | ALDH3A1 (0.56) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL4106460 | 0.76 | MEN1 (0.60) | MAPTMEN1KMT2ALMNAGSK3B | |
| SCHEMBL13846846 | 0.76 | MEN1 (0.60) | MAPTMEN1KMT2ALMNAGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252503-B1 | AMINOIMIDAZOQUINOLINE DERIVATIVES | Bristol-Myers Squibb Company (US) | 1992-11-19 | — | — | EP | disclosed |
| EP-0252503-A1 | Aminoimidazoquinoline derivatives | Bristol-Myers Squibb Company (US) | 1988-01-13 | — | — | EP | disclosed |
| US-4701459-A | 7-amino-1,3-dihydro-2H-imidazo[4,5-b]quinolin 2-ones and method for inhibiting phosphodiesterase and blood platelet aggregation | BRISTOL-MYERS COMPANY (US) | 1987-10-20 | — | — | US | disclosed |