Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ABHD10 | Q9NUJ1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16109527 | 0.83 | TDP1 (0.37) | CYP3A4CYP2C9PKMCYP2C19OPRM1 | |
| SCHEMBL18338919 | 0.76 | OPRM1 (0.47) | OPRM1MEN1KMT2A | |
| SCHEMBL320551 | 0.70 | HCAR3 (0.41) | OPRM1TDP1MEN1KMT2ALMNA | |
| SCHEMBL14967971 | 0.68 | TDP1 (0.40) | CYP3A4CYP2C9PKMCYP2C19OPRM1 | |
| SCHEMBL9692240 | 0.68 | MEN1 (0.43) | OPRM1MEN1KMT2A | |
| SCHEMBL14967612 | 0.68 | OPRM1 (0.37) | OPRM1TDP1ABHD10MEN1KMT2A | |
| SCHEMBL14968225 | 0.67 | IDO1 (0.31) | IDO1 | |
| SCHEMBL873001 | 0.67 | CYP3A4 (0.36) | CYP3A4CYP2C9PKMCYP2C19OPRM1 | |
| SCHEMBL16109919 | 0.66 | USP2 (0.37) | OPRM1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL17599636 | 0.66 | TDP1 (0.41) | CYP3A4CYP2C9PKMCYP2C19OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153692-B1 | METHOD FOR ISOMERIZATION A GLYCIDATE DERIVATIVE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-4621150-A | METAL PERHALATE OR SULFONATE OR COMPLEX; GLYCIDATE, 2-HYDROXY-3-BUTENOATE, EPOXIDE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-11-04 | — | — | US | disclosed |
| EP-0153692-A2 | Method for isomerization a glycidate derivative | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1985-09-04 | — | — | EP | disclosed |