Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15446338 | 0.88 | BACE1 (0.46) | TSHR | |
| SCHEMBL9026789 | 0.84 | TSHR (0.68) | TSHRNPC1RAB9A | |
| SCHEMBL30862345 | 0.84 | TSHR (0.68) | TSHRNPC1RAB9A | |
| SCHEMBL8856846 | 0.80 | BACE1 (0.52) | SLC6A4SLC6A3TSHRNPC1RAB9A | |
| SCHEMBL8573735 | 0.80 | BACE1 (0.52) | SLC6A4SLC6A3TSHRNPC1RAB9A | |
| SCHEMBL3201276 | 0.80 | BACE1 (0.52) | SLC6A4SLC6A3TSHRNPC1RAB9A | |
| SCHEMBL8503544 | 0.80 | BACE1 (0.52) | SLC6A4SLC6A3TSHRNPC1RAB9A | |
| SCHEMBL7141149 | 0.80 | BACE1 (0.52) | SLC6A4SLC6A3TSHRNPC1RAB9A | |
| SCHEMBL3201279 | 0.80 | BACE1 (0.52) | SLC6A4SLC6A3TSHRNPC1RAB9A | |
| SCHEMBL1692429 | 0.80 | TSHR (0.67) | SLC6A4SLC6A3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153692-B1 | METHOD FOR ISOMERIZATION A GLYCIDATE DERIVATIVE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-4621150-A | METAL PERHALATE OR SULFONATE OR COMPLEX; GLYCIDATE, 2-HYDROXY-3-BUTENOATE, EPOXIDE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-11-04 | — | — | US | disclosed |
| EP-0153692-A2 | Method for isomerization a glycidate derivative | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1985-09-04 | — | — | EP | disclosed |