SCHEMBL969249

SCHEMBL969249

C=Cc1ccc(N(c2cccc(C)c2)c2cccc(C)c2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.55
TP53 P04637 2/20 0.55
ALDH1A1 P00352 7/20 0.39
ACHE P22303 3/20 0.38
NPC1 O15118 3/20 0.36
CASP3 P42574 2/20 0.36
SENP8 Q96LD8 2/20 0.36
SENP7 Q9BQF6 2/20 0.36
SENP6 Q9GZR1 2/20 0.36
TSHR P16473 2/20 0.35
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
RAB9A P51151 2/20 0.34
RELA Q04206 1/20 0.34
NSD2 O96028 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
HTT P42858 1/20 0.33
GPX4 P36969 1/20 0.33
PAX8 Q06710 1/20 0.33
HSD17B1 P14061 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12909791 0.97 TDP1 (0.52) TDP1TP53ALDH1A1ACHENPC1
SCHEMBL5485483 0.97 TP53 (0.52) TDP1TP53ALDH1A1ACHENPC1
SCHEMBL12453662 0.97 TDP1 (0.52) TDP1TP53ALDH1A1ACHENPC1
SCHEMBL19244062 0.97 TDP1 (0.52) TDP1TP53ALDH1A1ACHENPC1
SCHEMBL5843443 0.97 TDP1 (0.52) TDP1TP53ALDH1A1ACHENPC1
SCHEMBL2602506 0.95 TDP1 (0.50) TDP1TP53ALDH1A1ACHENPC1
SCHEMBL766100 0.92 TDP1 (0.47) TDP1TP53ALDH1A1ACHENPC1
SCHEMBL12757056 0.92 TDP1 (0.47) TDP1TP53ALDH1A1ACHENPC1
SCHEMBL12858352 0.88 TDP1 (0.59) TDP1TP53ALDH1A1ACHENPC1
SCHEMBL14548354 0.88 TP53 (0.59) TDP1TP53ALDH1A1ACHENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276627-B2 One pot sequential reactions and novel products produced thereby IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2007-10-02 US claimed
US-20060224017-A1 One pot sequential reactions and novel products produced thereby IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2006-10-05 US claimed
US-10079343-B2 Organic el element and solution containing organic el material IDEMITSU KOSAN CO., LTD. (JP) 2018-09-18 US disclosed
US-9150496-B2 Condensed-cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-10-06 US disclosed
US-9150496-B2 Condensed-cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-10-06 US disclosed
US-9082995-B2 Organic EL element and organic EL material-containing solution IDEMITSU KOSAN CO., LTD. (JP) 2015-07-14 US disclosed
US-9054319-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2015-06-09 US disclosed
US-8912531-B2 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2014-12-16 US disclosed
US-8759819-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2014-06-24 US disclosed
US-20140131680-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-05-15 US disclosed
US-20140061627-A1 ORGANIC EL ELEMENT AND SOLUTION CONTAINING ORGANIC EL MATERIAL IDEMITSU KOSAN CO., LTD. (JP) 2014-03-06 US disclosed
US-20050221125-A1 Organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2005-10-06 US disclosed
US-6899961-B2 Organic electroluminescence device SAMSUNG SDI CO., LTD. (KR) 2005-05-31 US disclosed
US-6893775-B2 Battery having active material containing neutral carbon radical compound NEC CORPORATION (JP) 2005-05-17 US disclosed
US-20020168543-A1 ORGANIC ELECTROLUMINSCENT DEVICE NEC CORPORATION (JP) 2002-11-14 US disclosed
US-20020041996-A1 Battery having active material containing neutral carbon radical compound NEC CORPORATION (JP) 2002-04-11 US disclosed
US-20020022151-A1 Organic electroluminescent device NEC CORPORATION (JP) 2002-02-21 US disclosed
US-20010006742-A1 Organic electroluminescence device NEC CORPORATION 2001-07-05 US disclosed
US-20010006741-A1 Organic electroluminescent device NEC CORPORATION 2001-07-05 US disclosed
EP-1109235-A2 Organic electroluminescence device NEC CORPORATION (JP) 2001-06-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060224017-A1 One pot sequential reactions and novel products produced thereby PNMT, CYP1A1, TERT TDP1 1283/4885TP53 1575/4885ALDH1A1 602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.