Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SELL | P14151 | 1/20 | 0.40 |
| ▸ | SELP | P16109 | 1/20 | 0.40 |
| ▸ | SELE | P16581 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502457 | 0.99 | SMN1; SMN2 (0.42) | SMN1; SMN2HPGDL3MBTL1GAATDP1 | |
| SCHEMBL9505690 | 0.93 | L3MBTL1 (0.41) | SMN1; SMN2HPGDL3MBTL1GAATDP1 | |
| SCHEMBL9502293 | 0.92 | POLB (0.40) | SMN1; SMN2HPGDL3MBTL1GAATDP1 | |
| SCHEMBL9502202 | 0.90 | ACAT1 (0.41) | SMN1; SMN2HPGDL3MBTL1GAATDP1 | |
| SCHEMBL9502424 | 0.89 | ACAT1 (0.41) | SMN1; SMN2HPGDL3MBTL1GAATDP1 | |
| SCHEMBL9692436 | 0.84 | SMN1; SMN2 (0.39) | SMN1; SMN2HPGDL3MBTL1GAATSHR | |
| SCHEMBL9503835 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2HPGDL3MBTL1GAATDP1 | |
| SCHEMBL9506113 | 0.83 | SMN1; SMN2 (0.41) | SMN1; SMN2HPGDL3MBTL1GAATDP1 | |
| SCHEMBL9506112 | 0.83 | ACAT1 (0.39) | SMN1; SMN2HPGDL3MBTL1GAATDP1 | |
| SCHEMBL9692556 | 0.82 | HDAC3 (0.43) | SMN1; SMN2HPGDL3MBTL1GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992003412-A2 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |