Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9124632 | 0.86 | TSHR (0.58) | TSHRMEN1KMT2AHPGDRAB9A | |
| SCHEMBL9690575 | 0.86 | TSHR (0.49) | TSHRMEN1KMT2AHPGDRAB9A | |
| SCHEMBL9693018 | 0.82 | RAB9A (0.62) | TSHRMEN1KMT2AHPGDRAB9A | |
| Hydrochloric Acid SCHEMBL9124081 | 0.81 | TP53 (0.45) | TSHRMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL28020498 | 0.79 | ALDH1A1 (0.74) | TSHRMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL9124271 | 0.79 | RAB9A (0.47) | TSHRMEN1KMT2AHPGDRAB9A | |
| SCHEMBL9125661 | 0.79 | APEX1 (0.51) | TSHRMEN1KMT2AHPGDRAB9A | |
| SCHEMBL9124622 | 0.78 | TP53 (0.45) | TSHRRAB9AALDH1A1NPC1ADRB2 | |
| SCHEMBL9122797 | 0.77 | ALDH1A1 (0.44) | TSHRMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL9692380 | 0.76 | ALDH1A1 (0.41) | TSHRMEN1KMT2ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520552-A1 | Derivatives of (hetero) aromatic ethers and thioethers having antihyperlipidemic activity, process for their preparation and pharmaceutical compositions containing them | PIERREL S.p.A. (IT) | 1992-12-30 | — | — | EP | claimed |
| EP-0520552-A1 | Derivatives of (hetero) aromatic ethers and thioethers having antihyperlipidemic activity, process for their preparation and pharmaceutical compositions containing them | PIERREL S.p.A. (IT) | 1992-12-30 | — | — | EP | disclosed |