Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.53 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.52 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.52 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.52 |
| ▸ | DNPH1 | O43598 | 2/20 | 0.51 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9184520 | 0.93 | P2RX3 (0.62) | POLBENPP1P2RY1P2RX3P2RX2 | |
| SCHEMBL29450536 | 0.93 | P2RX3 (0.62) | POLBENPP1P2RY1P2RX3P2RX2 | |
| SCHEMBL15794921 | 0.92 | P2RX3 (0.63) | POLBENPP1P2RY1P2RX3P2RX2 | |
| SCHEMBL19699286 | 0.89 | POLB (0.53) | POLBENPP1P2RY1TAS1R3TAS1R1 | |
| SCHEMBL30888440 | 0.89 | POLB (0.51) | POLBENPP1P2RY1TAS1R3TAS1R1 | |
| SCHEMBL14399998 | 0.88 | P2RX3 (0.48) | POLBENPP1P2RY1TAS1R3TAS1R1 | |
| SCHEMBL7060363 | 0.87 | SLC29A1 (0.59) | SLC29A1 | |
| SCHEMBL19699271 | 0.86 | POLB (0.52) | POLBENPP1P2RY1TAS1R3TAS1R1 | |
| SCHEMBL216645 | 0.85 | P2RX3 (0.70) | P2RY1TAS1R3TAS1R1P2RX3P2RX2 | |
| SCHEMBL1042589 | 0.85 | POLB (0.54) | POLBENPP1P2RY1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203959-B1 | NUCLEOTIDE ANALOGS FOR NUCLEIC ACID LABELING AND DETECTION | LIFE TECHNOLOGIES, INC. (US) | 1992-09-09 | — | — | EP | disclosed |
| EP-0203959-A4 | NUCLEOTIDE ANALOGS FOR NUCLEIC ACID LABELING AND DETECTION. | LIFE TECHNOLOGIES INC (US) | 1989-08-09 | — | — | EP | disclosed |
| EP-0203959-A1 | NUCLEOTIDE ANALOGS FOR NUCLEIC ACID LABELING AND DETECTION. | LIFE TECHNOLOGIES INC (US) | 1986-12-10 | — | — | EP | disclosed |
| WO-1986002929-A1 | NUCLEOTIDE ANALOGS FOR NUCLEIC ACID LABELING AND DETECTION | LIFE TECHNOLOGIES, INC. (US) | 1986-05-22 | — | — | WO | disclosed |