SCHEMBL1042589

SCHEMBL1042589

C=C(C)CCNc1ncnc2c1ncn2[C@H]1C[C@H](O)[C@@H](COP(=O)(O)O)O1

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.54
DNPH1 O43598 2/20 0.53
TAS1R3 Q7RTX0 1/20 0.52
TAS1R1 Q7RTX1 1/20 0.52
P2RX3 P56373 1/20 0.52
P2RX2 Q9UBL9 1/20 0.52
ENPP1 P22413 2/20 0.51
P2RY1 P47900 2/20 0.51
P2RY12 Q9H244 1/20 0.49
SLC29A1 Q99808 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1044837 0.87 HIF1A (0.61) SLC29A1
SCHEMBL218771 0.86 DNPH1 (0.70) DNPH1TAS1R3TAS1R1P2RX3P2RX2
SCHEMBL29564165 0.86 DNPH1 (0.70) DNPH1TAS1R3TAS1R1P2RX3P2RX2
SCHEMBL31685649 0.86 POLB (0.59) POLBDNPH1TAS1R3TAS1R1ENPP1
SCHEMBL31685679 0.86 ADORA3 (0.62) POLBTAS1R3TAS1R1ENPP1P2RY1
SCHEMBL9693060 0.85 POLB (0.56) POLBDNPH1TAS1R3TAS1R1P2RX3
SCHEMBL19699247 0.84 POLB (0.53) POLBDNPH1TAS1R3TAS1R1P2RX3
SCHEMBL19699286 0.84 POLB (0.53) POLBDNPH1TAS1R3TAS1R1P2RX3
SCHEMBL19699222 0.84 POLB (0.55) POLBDNPH1TAS1R3TAS1R1ENPP1
SCHEMBL19699268 0.84 POLB (0.55) POLBDNPH1TAS1R3TAS1R1ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110300170-A1 HCV VACCINES INTERCELL AG (AT) 2011-12-08 US claimed
US-20110236414-A1 Bacterial Polysaccharide-Polypeptide Conjugate Compositions INTERCELL AG (AT) 2011-09-29 US claimed
JP-4734241-B2 2011-07-27 JP claimed
EP-2345420-A1 Use of a TH1 immune response inducing adjuvant for enhancing immune responses Intercell AG (AT) 2011-07-20 EP claimed
JP-4676426-B2 2011-04-27 JP claimed
EP-2275131-A2 HCV Vaccines Intercell AG (AT) 2011-01-19 EP claimed
US-7858588-B2 Immunostimulatory oligodeoxynucleic molecules INTERCELL AG (AT) 2010-12-28 US claimed
EP-1648502-B1 HCV VACCINES INTERCELL AG (AT) 2010-12-01 EP claimed
US-20100297170-A1 VACCINES VALNEVA AUSTRIA GMBH (AT) 2010-11-25 US claimed
US-20090155294-A1 HCV VACCINES BUSCHLE MICHAEL 2009-06-18 US claimed
US-20060263386-A1 Vaccine against infections with viral pathogens; an antigen, a peptide and an immunostimulatory deoxynucleic acid containing deoxyinosine and/or deoxyuridine residues INTERCELL AG (AT) 2006-11-23 US claimed
JP-2006521320-A 2006-09-21 JP claimed
EP-1648502-A2 HCV VACCINES Intercell AG (AT) 2006-04-26 EP claimed
EP-1608402-A1 IMPROVED VACCINES Intercell AG (AT) 2005-12-28 EP claimed
US-20050250716-A1 Immunostimulatory oligodeoxynucleotides INTERCELL AG 2005-11-10 US claimed
WO-2005004910-A2 HCV VACCINES INTERCELL AG (AT) 2005-01-20 WO claimed
US-20040248831-A1 Immunostimulatory oligodeoxynucleic molecules INTERCELL AG (AT) 2004-12-09 US claimed
WO-2004084938-A1 IMPROVED VACCINES INTERCELL AG (AT) 2004-10-07 WO claimed
EP-1296713-B1 IMMUNOSTIMULATORY OLIGODEOXYNUCLEOTIDES INTERCELL BIOMEDIZINISCHE FORSCHUNGS & ENTWICKLUNGS GMBH (AT) 2003-09-17 EP claimed
US-20030171321-A1 Immunostimulatory oligodeoxynucleotides VALNEVA AUSTRIA GMBH (AT) 2003-09-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110300170-A1 HCV VACCINES HAVCR2, CXCR3, CD81 POLB 2944/4885DNPH1 2265/4885TAS1R3 4000/4885
US-20100297170-A1 VACCINES DDX1, DHX15, DDX5 POLB 480/4885DNPH1 938/4885TAS1R3 3844/4885
US-20090155294-A1 HCV VACCINES HAVCR2, CD81, CD74 POLB 2293/4885DNPH1 3157/4885TAS1R3 4378/4885
US-20040248831-A1 Immunostimulatory oligodeoxynucleic molecules NT5C3B, UMPS, NT5C2 POLB 64/4885DNPH1 104/4885TAS1R3 4218/4885
US-20050250716-A1 Immunostimulatory oligodeoxynucleotides IFNG, TLR9, TSLP POLB 140/4885DNPH1 1163/4885TAS1R3 4635/4885
US-20110236414-A1 Bacterial Polysaccharide-Polypeptide Conjugate Compositions DDOST, NGLY1, DAD1 POLB 1153/4885DNPH1 633/4885TAS1R3 3811/4885
US-20060263386-A1 Vaccine against infections with viral pathogens; an antigen, a peptide and an immunostimulatory deoxynucleic acid containing deoxyinosine and/or deoxyuridine residues DUT, CD74, DDX5 POLB 612/4885DNPH1 454/4885TAS1R3 4391/4885
US-20030171321-A1 Immunostimulatory oligodeoxynucleotides NT5C3B, PNP, UMPS POLB 59/4885DNPH1 77/4885TAS1R3 4053/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.