Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 9/20 | 0.54 |
| ▸ | GHSR | Q92847 | 4/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | NPY1R | P25929 | 6/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024848 | 0.92 | GHSR (0.57) | XIAPGHSRAGTR1NPY1R | |
| SCHEMBL9405738 | 0.83 | XIAP (0.48) | XIAPGHSRAGTR1NPY1R | |
| SCHEMBL9024480 | 0.83 | GHSR (0.53) | XIAPGHSRAGTR1NPY1R | |
| SCHEMBL9405627 | 0.82 | GHSR (0.57) | XIAPGHSRAGTR1NPY1R | |
| SCHEMBL9023535 | 0.81 | GHSR (0.70) | XIAPGHSRAGTR1NPY1R | |
| SCHEMBL9694667 | 0.78 | NPY1R (0.54) | XIAPGHSRAGTR1NPY1R | |
| SCHEMBL9405575 | 0.78 | GHSR (0.56) | XIAPGHSRAGTR1NPY1R | |
| SCHEMBL9025936 | 0.78 | XIAP (0.60) | XIAPGHSRAGTR1NPY1R | |
| SCHEMBL9024221 | 0.77 | GHSR (0.78) | XIAPGHSRAGTR1NPY1R | |
| SCHEMBL9024214 | 0.77 | GHSR (0.78) | XIAPGHSRAGTR1NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513974-A1 | Novel benzo-fused lactams that promote the release of growth hormone | MERCK & CO. INC. (US) | 1992-11-19 | — | — | EP | disclosed |