Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28418700 | 0.81 | TRPA1 (0.53) | TRPA1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL14198039 | 0.78 | TRPA1 (0.55) | TRPA1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29042855 | 0.78 | TRPA1 (0.55) | TRPA1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6098478 | 0.76 | TRPA1 (0.48) | TRPA1ALDH1A1LMNAHDAC1HDAC8 | |
| SCHEMBL6098480 | 0.76 | TRPA1 (0.48) | TRPA1ALDH1A1LMNAHDAC1HDAC8 | |
| SCHEMBL10857084 | 0.75 | TRIM24 (0.52) | TRPA1ALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL11218459 | 0.75 | CXCL8 (0.46) | TRPA1LMNATSHRKMT2A | |
| SCHEMBL6332503 | 0.75 | TRPA1 (0.52) | TRPA1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6332502 | 0.75 | TRPA1 (0.52) | TRPA1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL27514144 | 0.75 | TRPA1 (0.52) | TRPA1ALDH1A1GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409689-A2 | A process for the purification of 1,1-bis(4-chlorophenyl)-2,2,2-trichloroethanol | ELF ATOCHEM S.A. (FR) | 1991-01-23 | — | — | EP | claimed |
| EP-0519807-A1 | Process for the dehydrochlorination of 1,1-bis(R-phényl)-2,2,2-trichloroethanes | ELF ATOCHEM S.A. (FR) | 1992-12-23 | — | — | EP | disclosed |