Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535861 | 0.85 | RIPK1 (0.42) | NPSR1PDK1PDK2PDK3PDK4 | |
| SCHEMBL28174957 | 0.85 | RIPK1 (0.42) | NPSR1PDK1PDK2PDK3PDK4 | |
| SCHEMBL10955639 | 0.83 | CYP2C19 (0.48) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL31052866 | 0.83 | MAPT (0.44) | NPSR1PDK1PDK2PDK3PDK4 | |
| SCHEMBL28730004 | 0.81 | MMP8 (0.50) | MAPTHPGDHSD17B10SMN1; SMN2EPHX2 | |
| SCHEMBL4513643 | 0.80 | MAPT (0.41) | NPSR1PDK1PDK2PDK3PDK4 | |
| SCHEMBL11390719 | 0.80 | MAPT (0.45) | NPSR1PDK1PDK2PDK3PDK4 | |
| SCHEMBL10765101 | 0.80 | GAA (0.48) | NPSR1MAPTGAASMN1; SMN2EPHX1 | |
| SCHEMBL23137093 | 0.76 | SMN1; SMN2 (0.48) | MAPTHPGDRAB9AHSD17B10SMN1; SMN2 | |
| SCHEMBL5411877 | 0.75 | NPSR1 (0.49) | NPSR1PDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507153-A2 | Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenyl-propionic acids | CELGENE CORPORATION (US) | 1992-10-07 | — | — | EP | disclosed |