SCHEMBL969378

SCHEMBL969378

C=C(C)C(=O)Oc1cc(C)cc(C(=O)O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 1/20 0.52
ELANE P08246 1/20 0.47
HCAR1 Q9BXC0 1/20 0.46
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
POLB P06746 2/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CNR2 P34972 1/20 0.38
ATM Q13315 1/20 0.38
HCAR2 Q8TDS4 1/20 0.37
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
LMNA P02545 1/20 0.35
PLA2G2A P14555 1/20 0.35
ALDH1A1 P00352 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
RAB9A P51151 2/20 0.34
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4863802 0.90 ELANE (0.53) TPMTELANEKMT2AMEN1POLB
SCHEMBL17044564 0.90 ELANE (0.53) TPMTELANEKMT2AMEN1POLB
SCHEMBL19157832 0.86 ELANE (0.47) TPMTELANEKMT2AMEN1HTT
SCHEMBL2431902 0.86 ELANE (0.47) TPMTELANEKMT2AMEN1HTT
SCHEMBL10148962 0.82 TPMT (0.59) TPMTELANEHCAR1KMT2AMEN1
SCHEMBL30031930 0.82 TPMT (0.59) TPMTELANEHCAR1KMT2AMEN1
SCHEMBL19335905 0.81 ELANE (0.45) ELANEKMT2APOLBAPEX1HTT
SCHEMBL15388887 0.79 ELANE (0.42) ELANEHCAR1KMT2AMEN1POLB
SCHEMBL1433687 0.78 TPMT (0.53) TPMTHCAR1KMT2AMEN1POLB
SCHEMBL15357797 0.78 ELANE (0.53) ELANEKMT2AMEN1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11111320-B2 Addition-fragmentation oligomers 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-09-07 US disclosed
EP-3326711-B1 GRAFT COPOLYMER FUNCTIONALIZED ARTICLE 3M INNOVATIVE PROPERTIES CO (US) 2021-07-07 EP disclosed
EP-2675783-B1 ADDITION-FRAGMENTATION AGENTS 3M INNOVATIVE PROPERTIES CO (US) 2020-04-22 EP disclosed
EP-3259323-B1 ADDITION-FRAGMENTATION OLIGOMERS 3M INNOVATIVE PROPERTIES CO (US) 2020-02-26 EP disclosed
US-20200031961-A1 ADDITION-FRAGMENTATION OLIGOMERS 3M INNOVATIVE PROPERTIES CO (US) 2020-01-30 US disclosed
US-10479848-B2 Addition-fragmentation oligomers 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-11-19 US disclosed
US-10471398-B2 Graft copolymer functionalized article 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-11-12 US disclosed
US-10370322-B2 Addition-fragmentation agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-08-06 US disclosed
EP-3502092-A1 ADDITION-FRAGMENTATION AGENTS 3M Innovative Properties Company (US) 2019-06-26 EP disclosed
US-10144760-B2 Ligand functional substrates 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-12-04 US disclosed
US-20030212210-A1 Reactive oligomers 3M INNOVATIVE PROPERTIES COMPANY 2003-11-13 US disclosed
US-6635690-B2 Step growth crosslinkable materials 3M INNOVATIVE PROPERTIES COMPANY 2003-10-21 US disclosed
US-20030114553-A1 Hardenable self-supporting structures and methods SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2003-06-19 US disclosed
US-20030096908-A1 Reactive oligomers 3M INNOVATIVE PROPERTIES COMPANY 2003-05-22 US disclosed
WO-2003015720-A1 HARDENABLE SELF-SUPPORTING STRUCTURES AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-02-27 WO disclosed
WO-2002102909-A1 REACTIVE OLIGOMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-12-27 WO disclosed
US-20020132927-A1 Pressure sensitive adhesives possessing high load bearing capability 3M INNOVATIVE PROPERTIES COMPANY 2002-09-19 US disclosed
US-6448337-B1 CURABLE SYRUP COMPRISING DUAL POLYMERS CONTAINING PENDANT INTERREACTIVE GROUPS, FREE RADICAL POLYMERIZABLE SOLVENT MONOMER AND PHOTOINITIATOR; BALANCED ADHESIVE AND COHESIVE CHARACTERISTICS 3M INNOVATIVE PROPERTIES COMPANY 2002-09-10 US disclosed
EP-1230315-A1 PRESSURE SENSITIVE ADHESIVES POSSESSING HIGH LOAD BEARING CAPABILITY 3M Innovative Properties Company (US) 2002-08-14 EP disclosed
WO-2002038694-A1 PRESSURE SENSITIVE ADHESIVES POSSESSING HIGH LOAD BEARING CAPABILITY 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-05-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10479848-B2 Addition-fragmentation oligomers ECPAS, ITGA8, NBAS TPMT 4639/4885ELANE 2991/4885HCAR1 4436/4885
US-10144760-B2 Ligand functional substrates PCNA, POLM, POLL TPMT 4554/4885ELANE 1666/4885HCAR1 2142/4885
US-10370322-B2 Addition-fragmentation agents NR4A1, PARP14, MTX1 TPMT 4728/4885ELANE 748/4885HCAR1 1302/4885
US-20200031961-A1 ADDITION-FRAGMENTATION OLIGOMERS ECPAS, ITGA8, NBAS TPMT 4639/4885ELANE 2991/4885HCAR1 4436/4885
US-11111320-B2 Addition-fragmentation oligomers ECPAS, ITGA8, NBAS TPMT 4639/4885ELANE 2991/4885HCAR1 4436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.