Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 2/20 | 0.33 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ITK | Q08881 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695012 | 0.88 | AURKA (0.39) | AURKAHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6481805 | 0.86 | AURKA (0.41) | AURKAHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9695823 | 0.86 | PDE2A (0.45) | AURKALMNAPDE5AALDH1A1NOS1 | |
| SCHEMBL9398067 | 0.83 | ATP4A (0.42) | HPGDNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL9693714 | 0.83 | HPGD (0.39) | AURKAHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9695028 | 0.82 | AURKA (0.39) | AURKAHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9695910 | 0.82 | AURKA (0.39) | AURKAHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9695861 | 0.79 | AURKA (0.40) | AURKAHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9695407 | 0.79 | HPGD (0.36) | AURKAHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9695113 | 0.77 | AURKA (0.43) | AURKAHPGDNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933458-A | ANTISECRETORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-06-12 | — | — | US | claimed |
| US-5106976-A | Antisecretory agents | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-04-21 | — | — | US | disclosed |
| EP-0234690-B1 | SULFOXIDE DERIVATIVES AND THEIR PREPARATION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-05-15 | — | — | EP | disclosed |
| US-4933458-A | ANTISECRETORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0234690-A1 | Sulfoxide derivatives and their preparation | NIPPON CHEMIPHAR CO., LTD. (JP) | 1987-09-02 | — | — | EP | disclosed |