Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | PDE5A | O76074 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695910 | 0.87 | AURKA (0.39) | AURKATP53SMN1; SMN2POLBNUDT1 | |
| SCHEMBL6481805 | 0.85 | AURKA (0.41) | AURKATP53SMN1; SMN2NUDT1HPGD | |
| SCHEMBL9693791 | 0.82 | AURKA (0.40) | AURKATP53SMN1; SMN2CYP2C9NUDT1 | |
| SCHEMBL9695012 | 0.81 | AURKA (0.39) | AURKATP53SMN1; SMN2CYP2C9NUDT1 | |
| SCHEMBL9695823 | 0.79 | PDE2A (0.45) | AURKATP53POLBCYP2C9MAPT | |
| SCHEMBL9695009 | 0.78 | PDE5A (0.38) | AURKATP53SMN1; SMN2NUDT1HPGD | |
| SCHEMBL9695897 | 0.77 | PDE5A (0.40) | AURKATP53SMN1; SMN2NUDT1HPGD | |
| SCHEMBL9695861 | 0.76 | AURKA (0.40) | AURKATP53SMN1; SMN2NUDT1HPGD | |
| SCHEMBL9695352 | 0.76 | PDE5A (0.38) | AURKATP53SMN1; SMN2CYP2C9NUDT1 | |
| SCHEMBL9395895 | 0.75 | ALDH1A1 (0.41) | TP53SMN1; SMN2KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933458-A | ANTISECRETORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-06-12 | — | — | US | claimed |
| US-5106976-A | Antisecretory agents | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-04-21 | — | — | US | disclosed |
| EP-0234690-B1 | SULFOXIDE DERIVATIVES AND THEIR PREPARATION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-05-15 | — | — | EP | disclosed |
| US-4933458-A | ANTISECRETORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0234690-A1 | Sulfoxide derivatives and their preparation | NIPPON CHEMIPHAR CO., LTD. (JP) | 1987-09-02 | — | — | EP | disclosed |