Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.44 |
| ▸ | MAOA | P21397 | 6/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1998501 | 0.78 | MAOB (0.40) | MAOBMAOAPTPN1FTOCA2 | |
| SCHEMBL10552764 | 0.78 | MAOB (0.40) | MAOBMAOAPTPN1FTOCA2 | |
| Benzene SCHEMBL28051570 | 0.77 | MAOB (0.42) | MAOBMAOAPTPN1FTOCA2 | |
| SCHEMBL31083783 | 0.74 | MAOB (0.41) | MAOBMAOAPTPN1FTOCA2 | |
| SCHEMBL25406806 | 0.74 | MAOB (0.41) | MAOBMAOAPTPN1FTOCA2 | |
| SCHEMBL97155 | 0.72 | MAOA (0.45) | MAOBMAOAFTOKDM4EALDH1A1 | |
| SCHEMBL2525949 | 0.72 | MAOB (0.51) | MAOBMAOAPTPN1CA2KDM4E | |
| SCHEMBL29366939 | 0.72 | MAOB (0.51) | MAOBMAOAPTPN1CA2KDM4E | |
| SCHEMBL276153 | 0.70 | MAOB (0.48) | MAOBMAOAPTPN1FTOCA2 | |
| SCHEMBL8769445 | 0.70 | MAOB (0.44) | MAOBMAOAPTPN1FTOCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994335-B2 | Electronically tuned ligands for asymmetric hydrogenation | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-09 | — | — | US | claimed |
| US-20100041898-A1 | Electronically Tuned Ligands For Asymmetric Hydrogenation | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-18 | — | — | US | claimed |
| WO-2008067218-A1 | ELECTRONICALLY TUNED LIGANDS FOR ASYMMETRIC HYDROGENATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-06-05 | — | — | WO | claimed |
| US-6316620-B1 | AS LIGANDS TO TRANSITION METALS WHICH ARE USED AS CATALYSTS IN SYNTHESIZING ASYMMETRIC COMPOUNDS TO OBTAIN SPECIFIC ENANTIOMERS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2001-11-13 | — | — | US | claimed |
| US-5663168-A | ADMINISTERING INHIBITORS OF HIV ASPARATATE PROTEASES | CIBA-GEIGY CORPORATION (US) | 1997-09-02 | — | — | US | claimed |
| EP-0626178-A1 | Use of inhibitors of HIV-protease for the treatment of tumorous diseases | CIBA-GEIGY AG (CH) | 1994-11-30 | — | — | EP | claimed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | claimed |
| EP-0532466-A2 | Derivatives of 5-amino-4-hydroxy-hexanoic acid and their therapeutical use | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | claimed |
| CN-114751883-A | Preparation method of benzofuran-3-carboxamide compound | 浙江理工大学 | 2022-07-15 | — | — | CN | disclosed |
| US-8394974-B2 | Process for producing optically active chromene oxide compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-03-12 | — | — | US | disclosed |
| US-8362252-B2 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-01-29 | — | — | US | disclosed |
| EP-1797082-B1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2012-08-29 | — | — | EP | disclosed |
| US-8212049-B2 | Electronically tuned ligands for asymmetric hydrogenation | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-07-03 | — | — | US | disclosed |
| EP-2426128-A1 | Carbostyril compound | Otsuka Pharmaceutical Co., Limited (JP) | 2012-03-07 | — | — | EP | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0532466-A2 | Derivatives of 5-amino-4-hydroxy-hexanoic acid and their therapeutical use | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041898-A1 | Electronically Tuned Ligands For Asymmetric Hydrogenation | BID, HDHD5, HRH4 | MAOB 2480/4885MAOA 2667/4885PTPN1 4520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.