Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9963329 | 0.82 | TDP1 (0.54) | TDP1KDM4EMAP2K1L3MBTL1PKM | |
| SCHEMBL24968313 | 0.80 | MAP2K1 (0.53) | TDP1KDM4EMAP2K1L3MBTL1PKM | |
| SCHEMBL16344365 | 0.80 | TDP1 (0.55) | TDP1KDM4EMAP2K1L3MBTL1PKM | |
| SCHEMBL27497542 | 0.78 | TDP1 (0.50) | TDP1KDM4EMAP2K1L3MBTL1PKM | |
| SCHEMBL18551398 | 0.75 | TDP1 (0.47) | TDP1KDM4EMAP2K1L3MBTL1PKM | |
| SCHEMBL2036100 | 0.73 | TDP1 (0.49) | TDP1KDM4EL3MBTL1PKMPOLB | |
| SCHEMBL812065 | 0.73 | KDM4E (0.59) | TDP1KDM4EMAP2K1L3MBTL1PKM | |
| SCHEMBL29906660 | 0.72 | TDP1 (0.45) | TDP1KDM4EMAP2K1L3MBTL1PKM | |
| SCHEMBL2800466 | 0.72 | L3MBTL1 (0.54) | TDP1KDM4EMAP2K1L3MBTL1PKM | |
| SCHEMBL107721 | 0.72 | KDM4E (0.57) | TDP1KDM4EMAP2K1L3MBTL1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277661-B1 | IMIDAZOPYRROLOPYRIDINES AND CONDENSED DERIVATIVES THEREOF USEFUL IN THE PREPARATION OF HERBICIDAL COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1992-09-16 | — | — | EP | disclosed |
| EP-0133309-B1 | HERBICIDES AND METHOD FOR THE PREPARATION THEREOF | AMERICAN CYANAMID COMPANY (US) | 1989-11-23 | — | — | EP | disclosed |
| EP-0133310-B1 | IMIDAZOLIDINONES, AND IMIDAZOLIDINETHIONES, PROCESS FOR THE PREPARATION THEREOF, AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1988-09-14 | — | — | EP | disclosed |
| EP-0277661-A1 | Imidazopyrrolopyridines and condensed derivatives thereof useful in the preparation of herbicidal compounds | AMERICAN CYANAMID COMPANY (US) | 1988-08-10 | — | — | EP | disclosed |
| US-4701208-A | Dihydroimidazopyrrolopyridine, quinoline, thieno- and furo[2,3-b]pyridine, dihydrothieno- and furo[2,3-b]-pyridine, thieno- and furo[3,2-b]pyridine and dihydrothieno- and furo[3,2-b]pyridine herbicides and method for preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1987-10-20 | — | — | US | disclosed |
| US-4608079-A | Imidazolidinones, and imidazolidinethiones, process and intermediates for the preparation thereof, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1986-08-26 | — | — | US | disclosed |
| EP-0133310-A1 | Imidazolidinones, and imidazolidinethiones, process for the preparation thereof, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1985-02-20 | — | — | EP | disclosed |
| EP-0133309-A1 | Herbicides and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1985-02-20 | — | — | EP | disclosed |