Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694278 | 0.85 | LMNA (0.50) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL11591288 | 0.84 | ALDH1A1 (0.56) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL11591282 | 0.84 | ALDH1A1 (0.56) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL4629990 | 0.82 | LMNA (0.54) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL4629991 | 0.82 | LMNA (0.54) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL4629992 | 0.82 | LMNA (0.54) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL4630600 | 0.82 | LMNA (0.54) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL11591693 | 0.82 | LMNA (0.54) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL6129232 | 0.80 | LMNA (0.54) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL6129231 | 0.80 | LMNA (0.54) | LMNANR1I2ABCB11ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120841-A | Antibiotics for easy absorption | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0128029-B1 | CEPHALOSPORIN ESTER DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1989-02-08 | — | — | EP | disclosed |
| EP-0128029-A2 | Cephalosporin ester derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1984-12-12 | — | — | EP | disclosed |